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Diosgenin Powder
2.Appearance: Off-White Powder
3.Specification: 98% Diosgenin
4.CAS NO: 512-04-9
5.Packing Specification: 25kg/drum, 27 drums/tray
6.Delivery: 3-7working days
7.Main Market: Europe, America, Vietnam, Indonesia, Southeast Asia, Thailand, Russia, etc.
8.Certification: KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.
- Product Description
Premium Diosgenin Powder for Pharmaceutical Manufacturing | High Purity Bulk Supply
When looking for a reliable supplier of diosgenin powder, quality and stability are essential. Shaanxi Hongda, a reputable manufacturer with over 25 years of experience, provides pharmaceutical-grade diosgenin with a purity greater than 98%, fully compatible with applicable standards, to suit your hormone production requirements. Our technique eliminates trace heavy metals and superfluous moisture, ensuring product dissolving rate and reaction yield by controlled acid hydrolysis and a three-stage solvent recovery technology.
Diosgenin is a critical bioactive ingredient extracted from Dioscorea species, working as a major precursor in creating steroid hormones including progesterone, corticosteroids, and testosterone. Our 98%+ HPLC-verified Diosgenin fulfils rigorous pharmacopeial standards (USP/EP), delivering optimal purity for pharmaceutical formulae. With fully integrated sourcing and cGMP-certified production, we offer scalable quantities appropriate to your API manufacturing demands.
Product Highlights That Set Us Apart
Extreme Moisture and Solvent Control: Our Diosgenin maintains a strict loss on drying (LOD) below 0.5% and employs a vacuum nitrogen-filled secondary packaging process, ensuring no secondary drying is required during laboratory or factory feeding, directly improving the first-time success rate of the reaction.
"Zero Benzene" Environmentally Friendly Process: We have completely abandoned traditional benzene-containing solvent systems, opting instead for a pharmaceutical-grade ethanol recycling process. This allows your end products (such as progesterone and birth control pills) to easily pass FDA or EMA Category A solvent residue reviews.
Optimized Physical Crystallization Form: We provide both needle-like crystals and powder forms to fulfill your different product requirements.
Our diosgenin goes through rigorous high-performance liquid chromatography (HPLC) testing, resulting in a purity of more than 98%. This steroid hormone precursor is an excellent starting material for the manufacture of birth control pills, corticosteroids, and estrogen/testosterone derivatives.
We have scalable production capability to satisfy needs at varied scales while adhering to API and current Good Manufacturing Practice (cGMP) guidelines.
Product Specification
Items | Standards | Results |
Physical Analysis | ||
Appearance | Fine Powder | Conforms |
Color | White Powder | Conforms |
Odor | Characteristic | Conforms |
Mesh Size | 100% through 80 mesh size | Conforms |
General Analysis | ||
Identification | Identical to R.S. sample | Conforms |
Diosgenin | ≥98% | 98.8% |
Extract Solvents | Water and Ethanol | Conforms |
Loss on Drying (g/100g) | ≤5.0 | 3.24% |
Ash(g/100g) | ≤5.0 | 2.05% |
Chemical Analysis | ||
Pesticides Residue (mg/kg) | 0.05 | Conforms |
Residual Solvent | <0.05% | Conforms |
Residual Radiation | Negative | Conforms |
Lead(Pb) (mg/kg) | <3.0 | Conforms |
Arsenic(As) (mg/kg) | <2.0 | Conforms |
Cadmium(Cd) (mg/kg) | <1.0 | Conforms |
Mercury(Hg) (mg/kg) | <0.1 | Conforms |
Microbiological Analysis | ||
Total Plate Count(cfu/g) | ≤1,000 | 300 |
Molds and Yeast (cfu/g) | ≤100 | 29 |
Coliforms (cfu/g) | Negative | Conforms |
Salmonella(/25g) | Negative | Conforms |
Applications in Pharmaceutical Manufacturing
Diosgenin has numerous significant functions in current pharmaceutical manufacture. Your manufacturing procedures can exploit this versatile material for creating oral contraceptives, notably progesterone derivatives that require consistent potency.
The molecule shines as a raw material for corticosteroid anti-inflammatory drugs, where purity strongly effects therapeutic efficacy. You may also employ it as a basic chemical for hormone replacement therapies, guaranteeing your HRT items satisfy regulatory criteria and patient safety standards.
✅ Why Partner With Us?
Quality Assurance
- FDA/EMA-aligned facilities with ISO 22000 certification.
- Stability testing confirms 24-month shelf life under recommended storage.
Sustainable Sourcing
- Eco-friendly extraction reduces solvent waste by 30%.
- Ethically harvested Dioscorea roots with FairWild options.
Global Compliance
- REACH, WHO-GMP, and Kosher/Halal certifications available.
- DDP shipping ensures hassle-free customs clearance.
📦 Request a Quote or Sample
For B2B Buyers:
- ✅ Free Lab Samples: Test our Diosgenin Powder in your formulations.
- ✅ Bulk Pricing: Volume discounts for 500kg+ orders.
- ✅ Customization: Tailored particle size, packaging, or solubility profiles.
Contact our team: Email duke@hongdaherb.com for COAs, technical data, or formulation support.
🏆 Trusted By 200+ Global Clients
Industries We Serve:
- Pharmaceutical API Manufacturers
- Nutraceutical Brands
- Cosmetic Innovators
Certifications:
- cGMP | ISO 9001 | FDA | FairWild
Trust Signals That Matter
Our focus to quality goes beyond manufacturing to developing enduring collaborations with pharmaceutical firms globally. We preserve regulatory compliance marks like cGMP, ISO certifications, and adherence to US/EU pharmacopeia requirements.
Since 2008, we've serviced over 200 B2B clients spanning pharmaceuticals, nutraceuticals, and cosmetics sectors. Our solid track record indicates reliability and technical knowledge that you can rely on for your most crucial projects.
Client reviews consistently emphasise our supply chain dependability and commitment to assisting improve hormone API manufacturing operations.
Customized Packaging and Repackaging
We support flexible switching from 100g laboratory packs to 25kg/50kg industrial bulk packaging, and offer optional cryogenic transportation solutions based on your storage conditions.
FAQ
Q: Is your diosgenin extracted from yam or Dioscorea zingiberensis (yellow turmeric)?
A: To ensure a purity of over 98% and a stable C25 stereochemistry, we primarily use **Dioscorea zingiberensis (yellow turmeric)** as the source. This source has a higher diosgenin content, and associated impurities are more easily removed during purification.
Q: If I need to perform subsequent degradation, can you guarantee the clear color of your product during the acetylation reaction?
A: We use a secondary decolorization process with activated carbon to ensure the powder is pure white to the eye. During your acetylation reaction, due to the extremely low acid value and moisture content, the reaction solution will remain clear, without any troublesome gum-like substances or black spots.
Q: How is your Diosgenin verified for purity?
A: Each batch undergoes HPLC and GC testing to ensure ≥98% purity and <10 ppm heavy metals.
Q: Can I request Diosgenin optimized for topical corticosteroids?
A: Yes! We customize particle sizes (80-120 mesh recommended) for enhanced dermal absorption.
Q: Are stability studies available?
A: Full ICH-compliant stability data (24 months at 25°C/60% RH) is provided with every order.
Q: What documentation accompanies shipments?
A: COA, MSDS, cGMP certificates, and export permits are included.
Optimize Your Hormone API Supply Chain
Ready to secure your pharmaceutical supply chain? Contact our specialists at duke@hongdaherb.com for personalized pricing and technical support for your diosgenin powder requirements.
