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S Adenosyl Methionine Powder
2、Specification:99% HPLC
3、Appearance: White Powder
4、CAS NO.: 485-80-3
5、Lead time: 3-7 Working Days
6、Package: 12kg/drum, 27 drums/tray
7、Main Market: North America, Europe, Switzerland, South Africa, Southeast Asia, Australia, etc.
8、Certification: cGMP,Kosher, Halal, BRC, Organic, ISO9001, ISO22000, etc
9、Europe Warehouse/America Warehouse
- Product Description
Premium S-Adenosyl Methionine (SAMe) Powder | cGMP Certified | >99% Purity
Shaanxi Hongda Phytochemistry Co., Ltd. is one of the best companies that makes high-quality nutraceutical components, with a focus on S-Adenosyl Methionine Powder that is very pure. utilizing pharmaceutical-grade L-methionine and ATP, we make this important methyl donor utilizing modern fermentation technology. Our 6-step process makes sure that the quality is high:
- Fermentation: growing a unique strain of microbes
- Biosynthesis: Enzymatic change in a regulated setting
- Extraction: isolating at low temperatures to keep potency
- Purification: chromatography with more than one step
- Stabilization: a system that protects against free radicals
- QC Testing: Checking the purity of HPLC (≥99%)
Some of the best things about our S-Adenosyl Methionine Powder are:
- ≥99% purity (according to USP/EP standards) and <0.5% impurities
- Better stability: packaging that doesn't let oxygen in
- cGMP, ISO 9001, and FDA DMF are examples of global certifications.
- Better bioavailability: optimized distribution of particle size
- Batch consistency: potency can vary by up to 2%
- A full Certificate of Analysis (HPLC/GC-MS) is included with each batch.
- Reports on residual solvents (less than 500 ppm ethanol)
- Results of microbial testing that follow USP <61>
If you need technical specs or bulk pricing (minimum order quantity of 1 kg), please email our experts at duke@hongdaherb.com.
What are the benefits of partnering with us for SAMe production?
✅ Certified Excellence
- Halal/Kosher, GMP, ISO 9001, and NSF certifications
- Meets the standards set by the USP-NF (USA), EP (Europe), and JP (Japan) pharmacopeias
- Full FDA DMF and EU CEP documentation support
✅ Uncompromised Quality
- Because it was manufactured with contemporary fermentation methods, wine is 99.3% to 99.8% pure.
- There are not many heavy metals or endotoxins in it (less than 0.05 EU/mg).
- You can keep a package that has been cleansed with nitrogen for 24 months.
✅ Solutions for Every Market
- North America: SAMe for dietary supplements (depression, osteoarthritis)
- Europe: Pharma-grade SAMe for liver health formulations
- Asia: Cost-optimized SAMe for generics and OTC products
Technical Specifications
Item of Test | Limits of Test | Results of Test |
Appearance | Off-White Powder | Conform |
Assay by HPLC | ≥95% | 99.5% |
Sulphated Ash | ≤0.5% | 0.1% |
Water | ≤3% | 1.5% |
S, S-Isomer (HPLC) | ≥75% | 81% |
SAM-e ION (HPLC) | 49.5 - 54.7% | 51.5% |
P-Toluenesulfonic Acid | 21.0%–24.0% | 22.8% |
Content of Sulfate (SO4) (HPLC) | 23.5%–26.5% | 25.4% |
S-Adenosyl-L-Homocysteine | ≤1.0% | 0.05% |
Adenine | ≤1.0% | 0.3% |
Methylthioadenosine | ≤1.5% | 0.2% |
Adenosine | ≤1.0% | 0.01% |
Total Impurities | ≤3.5% | 1.1% |
Solubility | Free solubility in water | Complies |
Particle Size | 100% through 60 mesh | Complies |
Lead(mg/kg) | ≤3.0 | Complies |
Arsenic(mg/kg) | ≤2.0 | Complies |
Cadmium(mg/kg) | ≤1.0 | Complies |
Mercury (mg/kg) | ≤0.1 | Complies |
Total Plate Count | ≤1000cfu/g | Complies |
Mold &Yeast | ≤100cfu/g | Complies |
E．Coli | Not Detected | Complies |
Salmonella | Not Detected | Complies |
| Conclusion | Compliance With USP 43 | |
Primary Applications
1. Mental Health Formulations
- - Depression and mood disorder supplements
- - Cognitive function enhancement
2. Liver Support Products
- - Detoxification and liver function formulas
- - NAFLD (Non-Alcoholic Fatty Liver Disease) management
3. Joint Health Solutions
- - Osteoarthritis pain management
- - Cartilage support formulations
4. Specialty Nutraceuticals
- - Methylation support supplements
- - Anti-aging and longevity products
Our Quality Promise
✅ 99.9% SAMe content via HPLC testing shows that the product is of pharmaceutical grade.
✅ The formula is stabilized, and the packaging protects it from oxidation, which is a common problem with SAMe.
✅ Sourcing ethically: made from non-GMO plants that are safe for vegans.
Certifications
Ordering & Support
- - Minimum order quantity (MOQ): 1 kg for samples used in research and development and 100 kg or more for bulk manufacture.
- - We take two to three weeks to process standard orders.
- - Free Samples: Available with complete analytical documentation
FAQ
Q: How do you keep SAMe stable when it's in powder form?
A: Our unique stabilization method involves vacuum drying and processes that don't add antioxidants. When stored at 15–25°C, it only loses <2% of its value after 24 months.
Q: Can you make SAMe blends that work with enteric-coated tablets?
A: Yes! We sell pre-mixed SAMe with Eudragit® L100-55 or cellulose-based coatings that dissolve in a way that meets USP <711> standards.
Q: What testing is included in the Certificate of Analysis?
A: Every batch includes:
- Purity (HPLC)
- Heavy metals (ICP-MS)
- Residual solvents (GC)
- Microbial analysis (USP <61>)
Q: Do you support small trial orders?
A: Absolutely. We provide 100g–1kg samples with full documentation for R&D evaluation.
Ready to Elevate Your SAMe Formulations?
🌐 Global Reach: our US/EU/Asia warehouses
💡 Expert Support: Free formulation consulting and regulatory guidance
Contact Us Today
📧 Email: duke@hongdaherb.com
[Request a Sample] [Download Technical Dossier]
Key Differentiators in Every Gram of Our SAMe
- Stability: Does better than competitors in tests that speed up aging (40°C/75% RH)
- Traceability: a complete history of the raw materials from fermentation to packaging
- Sustainability: Packaging that can be recycled 100% and delivery that doesn't add to carbon emissions
For S-Adenosyl Methionine Powder that turns formulation problems into market-ready successes, choose Hongda. Let’s build the next generation of SAMe-powered solutions together!
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