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Spermidine Powder

1.English Name: Spermidine
2.Appearance: Light yellowish powder
3.Specification: 99%
4.CAS NO: 124-20-9
5.Packing Specification: 12kg/drum, 27 drums/tray
6.Delivery: 3-7working days
7.Main Market: North America, Europe, Switzerland, South Africa, Southeast Asia, Australia, etc.
8.Certification: KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.
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  • Product Description

Shaanxi Hongda Phytochemistry Co., Ltd. makes high-quality spermidine powder.

Shaanxi Hongda Phytochemistry Co., Ltd. is one of the leading companies producing high-purity spermidine powder. Shaanxi Hongda is a 25-year health food raw material research and development company. Our spermidine powder uses non-GMO microbial fermentation technology to make our spermidine pure powder more bioavailable and more stable. The first step in the production process is to select the right strain, and then the whole process includes precise fermentation, extraction and multi-step purification to achieve a purity of ≥99% (verified by high-performance liquid chromatography (HPLC)). 

Shaanxi Hongda's spermidine bulk powder is made from strictly selected non-GMO wheat germ. We employ our core "ultrasound-assisted supercritical extraction + multi-stage gradient purification" technology, ensuring that spermidine levels are far higher than industry-leading levels while fully preserving the natural polyamine microenvironment that promotes cell health.

Here are some of the best aspects about our spermidine powder:
  • High Purity: HPLC testing reveal that the amount of spermidine is at least 99%.
  • To make sure the quality is high, each batch comes with a Certificate of Analysis (COA) that shows the levels of heavy metals, residual solvents, and microbes.
  • Global Certifications: This product meets the standards set by cGMP, ISO 9001, and USP/EP. You can get the FDA Drug Master File (DMF).
  • Stability: It lasts a long time and can be kept in sealed packaging at -20°C.
  • Great for vitamins that help with aging, research on neurological illnesses, and formulae that speed up autophagy.

certifications

For researchers and producers looking for high-quality Spermidine Powder, we have:

  • Particle sizes can be changed (10–200µm).
  • You can buy in bulk (up to 1000 kg) and get savings on the volume.
  • Regulatory help for clinical studies and making things for sale.

If you want samples, technical information, or to talk about a cooperation, please email us at duke@hongdaherb.com. Shaanxi Hongda is the best place to get high-quality spermidine powder that is backed by science.

Spermidine powder

 

Why Choose Our Spermidine Powder?

  • 99%+ Purity: Third-party validated for heavy metals (<10ppm) and residual solvents.
  • Global Compliance: We provide pre-made FDA/EMA paperwork and assistance with DMF.
  • Scalable Sourcing: We can handle everything from 10kg clinical quantities to multi-ton commercial contracts.
  • Stable: It will last for 36 months if stored according to ICH guidelines.
  • Custom Formats: Adjust particle size (10-200µm) or request blended formulations.

 

Technical Specifications

Item of Analysis
Specification
Results
Identification
Consistent with the reference substance main peak retention time
Conforms
Color
White to Light Yellow Powder
 
Specific rotation [α]D20
+20.0°to +22.0°
+21.1°
Heavy metals
≤ 10ppm
Conforms
pH
7.5 to 8.5
8.1
Loss on drying
≤ 1.0%
0.05%
Residue on ignition
≤ 0.10%
0.04%
Lead
≤ 3ppm
Conforms
Arsenic
≤ 1ppm
Conforms
Mercury
≤ 0.1ppm
Conforms
Cadmium
≤ 1ppm
Conforms
Melting point
250.0℃ to 265.0℃
254.7℃ to 255.7℃
Hydrazine
≤ 2ppm
Conforms
Bulk density
-------
0.33g/ml
Tapped density
-------
0.54g/ml
L-Histidine
≤ 0.3%
0.08%
Assay
99.0% to 101.0%
99.6%
Total aerobes counts
≤ 1000cfu/g
30 cfu/g
Yeast and Mould
≤ 100cfu/g
40cfu/g
E.Coli
Negative
Negative Detectable
Salmonella
Negative
Negative Detectable

Cellular Housekeeping: Real Benefits

1. Autophagy works less well as we become older. Studies in people show that taking spermidine supplements:

  • Turns on genes that are associated to autophagy by up to 30%
  • Helps keep your mitochondria healthy so you can keep getting energy.
  • Encourages a healthy reaction to inflammation

2. Heart and brain health

  • New studies show that using spermidine can improve the flexibility of the cardiovascular system.
  • Keeping neurons safe from oxidative stress

spermidine benefits

 

Applications in Modern Therapeutics

Our spermidine powder powers breakthroughs in:

  • Senolytic Drug Development: Induce autophagy to clear senescent cells.
  • Neuroprotection: Target pathways in Alzheimer’s/Parkinson’s research.
  • Nutraceuticals: Formulate anti-aging supplements with proven bioavailability.

 

Quality Beyond Compliance

  • Full Traceability: Seed-to-batch genealogy reports.
  • Audit-Ready: Annual third-party facility inspections.
  • R&D Synergy: Co-develop derivatives like Spermidine Trihydrochloride.

quality assurance

Bulk Order

Priority Production: Reserved fermentation capacity for urgent timelines.

Dedicated Support: 24/7 account manager + QC team access.

Global Logistics: Cold-chain shipping to 50+ countries.

Our packaging

Formulation Empowerment Service

Our technical department provides the "2026 Spermine Synergistic Formulation Model" free of charge, such as synergistic solutions of spermine with quercetin and berberine, to help your product stand out in clinical feedback.

OEM service

FAQ

1. How is purity verified for Spermidine Powder?

Each batch undergoes HPLC, GC-MS, and ICP-MS testing, with results included in the COA.

2. Do you provide USP/EP-compliant grades?

Yes—we offer USP-NF monograph alignment for FDA submissions.

3. What fermentation methods are used?

Proprietary microbial strains ensure high yield (≥8g/L) and minimal endotoxins.

4. Can I get stability data for humid climates?

We provide ICH Zone IVb condition testing upon request.

5. Is there a minimum order for custom particle sizes?

Custom milling requires a 25kg minimum.

6. How quickly can you ship to Europe?

Express air freight available (5-7 days with customs pre-clearance).

 

Ready to Source Premium Spermidine Powder?

Email: duke@hongdaherb.com

Disclaimer: For pharmaceutical/cosmetic use only. Not for direct consumer sale.

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