Berberine Powder Bulk
2.Appearance: Light Yellow Powder
3.Specification: Berberine Hydrochloride 97%
4.Test Method: HPLC
5.CAS NO: 2086-83-1
6.Main Market: Europe, America, Vietnam, Indonesia, Southeast Asia, Thailand, Russia, etc.
7.Packing Specification: 25kg/drum, 27 drums/tray
8.Delivery: 3-7working days
9.Certification: KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.
- Product Description
Premium Berberine Powder Bulk for Pharmaceutical Excellence
Since 2003, Shaanxi Hongda Phytochemistry Co., Ltd. has been dedicated to the production of Plant Extracts and is one of the largest companies in this field. The company holds numerous well-known certifications, including ISO, Kosher, Halal, BRC, Organic, and FDA registration, proving that Hongda's berberine powder bulk absolutely meets global safety and quality standards. Berberine extract is renowned for its efficacy in treating digestive system diseases and regulating blood sugar. For 97% or 98% berberine hydrochloride, please contact us:duke@hongdaherb.com.
Shaanxi Hongda insists on extracting berberine hydrochloride powder from high-quality Phellodendron amurense extract or Coptis chinensis extract. We use core polar gradient extraction + multi-stage recrystallization technology to ensure that the purity of berberine hydrochloride is consistently greater than or equal to 98%, retaining trace amounts of active alkaloids from the plant. Clinical feedback shows that it exhibits better intestinal tolerance and higher AMPK activation efficiency.
Product Process
The first step in the production process is the selection and cleaning of raw materials. Then, in a fully enclosed, high-tech working environment, solvents are removed using ethanol or water to avoid contamination. Next, several steps are required to purify the powder, such as using chromatography or crystallization. Finally, the powder is dried in a controlled environment to make it fine and uniform. Strict standard operating procedures (SOPs) ensure that all steps are performed in the cleanest and most efficient manner.

What Makes Our Bulk Berberine HCl Different
- Extreme control of heavy metals and pesticide residues:
Utilizing an ICP-MS detection system, we strictly control lead (Pb) and mercury (Hg) levels to < 0.1 ppm, fully complying with US California Prop 65 and EU EC 396/2005 standards.
- Precisely customized physical specifications:
We offer a variety of specifications for different dosage forms:
High-Density Granular: Suitable for fully automated high-speed capsule filling, reducing dust spillage.
Micronized Powder: Improves tablet hardness and dissolution.
- 100% Authenticity Guaranteed:
HPTLC fingerprinting is available for every batch. We are committed to 100% plant-based ingredients, strictly prohibit the addition of illegal synthetic raw materials, and ensure the regulatory compliance of our products worldwide.

Globally Compliant Production
- ✔️ cGMP, ISO 9001 & ISO 22000 Certified Facilities
- ✔️ FDA-DMF & EU CEP Documentation Support
- ✔️ Halal/Kosher/Organic Certifications Available

Product Parameters
Item | Specification | Result |
Assay | ≥98% | 98.44%. |
Loss on drying | ≤12% | 11.31% |
Ignition residue | ≤0.2% | 0.18% |
Characters | Yellow crystalline powder,inodorous,extreme bitter | Confirms |
Identification | Be positive reaction under test procedures | Confirms |
Other alkaloid | Comply with the hygiene requirements | Confirms |
Total bacterial | ≤1000CFU/g | Confirms |
Total fungus | ≤100CFU/g | Confirms |
Colibacillus | None | Confirms |
Salmonella | None | Confirms |
Conclusion | Conform with specification. | |
Storage | Store in a cool dry place and keep away from strong light and heat. | |
Shelf life | 24 months when properly stored. | |
Trusted by 200+ Pharma Innovators Worldwide
Precision-Engineered for Critical Applications
1. Diabetes Management
Activates AMPK pathways with clinically validated glucose metabolism support
2. GI Therapeutics
Reduces intestinal inflammation while balancing gut microbiota
3. Antimicrobial Blends
Berberine Powder Bulk can enhances drug efficacy against resistant bacterial/viral strains
4. Custom Formulations
Available in 20-200µm particle sizes or delayed-release matrix blends

Uncompromising Quality Assurance
From Farm to Formula
- Seeds that can be tracked: raw materials from organic farms in Sichuan were tracked using GPS.
- Protocol for three tests: safety (ICP-MS), purity (GC-MS), and identity (HPLC).
- 36-Month Stability: Real-time & accelerated aging data included

Certification
Multiple international certifications guarantee product excellence and safety.

Flexible Bulk Ordering Made Simple
Seamless Procurement
- MOQ Options: Start at 25 kg and go up to container-load amounts
- Packaging: HDPE barrels that keep moisture out or foil bags that are cleansed with nitrogen
- Fast Logistics: cold-chain options for tropical regions
First-Time Buyer Perks
- ✅ Free Sample + Full Documentation
- ✅ Regulatory Submission Guidance
- ✅ 24/7 Technical Support via Email/WhatsApp

Answers for Informed Decisions
Your Berberine Sourcing Questions Solved
Q: How do you ensure that every batch is the same?
A: As an ISO 17025-accredited lab, we do 12 quality tests, which range from DNA testing of raw herbs to uniformity analysis of the finished blend.
Q: Can I get berberine powder bulk optimized for delayed-release tablets?
A: Yes! We co-process with pH-sensitive polymers for targeted intestinal absorption.
Q: What documentation supports regulatory filings?
A: Each shipment includes COA, TDS, ICH stability data, and GMP declaration.
Ready to Upgrade Your Berberine Supply?
Email Us Today at duke@hongdaherb.com
- Get a Custom Quote Within 24 Hours
- Request Free Sample & Technical Dossier
- Discuss Volume Discounts & JIT Delivery


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