Huperzine A Bulk Powder
2.Specification: Huperzine A 1%/99%
3.Test Method: HPLC
4.Appearance: White Fine Powder
5.CAS NO: 102518-79-6
6.Main Market: North America, Europe, Switzerland, South Africa, Southeast Asia, Australia, etc.
7.Packing specification: 12kg/drum, 27 drums/tray
8.Delivery: 3~7working days.
9.Certification: cGMP,FSSC,Kosher,Halal,BRC,Organic,FDA,ISO9001,ISO22000 etc.
- Product Description
Huperzine A Bulk Powder | Natural Huperzia Serrata Extract Factory Supplier
Huperzine‑A Bulk Powder – Natural Huperzia Serrata Extract For Dietary Supplement Manufacturing
Many buyers learn the hard way with Huperzine A Bulk Powder. Standard HPLC reports can look convincing, yet batches may contain synthetic racemic mixture instead of natural (-)‑huperzine‑A. You only spot this problem after you’ve finished blending, wasting raw material and production runs. As a Chinese manufacturer with 26‑year export background, we produce huperzine‑A strictly from wild‑managed Huperzia serrata, and run chiral‑phase testing to confirm active natural isomer for every lot.
Huperzia serrata extract comes as a bulk powder with a purity of 95% to 98%. It is a thin powder that is white to brown and easily dissolves in DMSO (30 mg/mL).
- Source:Whole herb of Huperzia serrata
‑ Available grades:1% standardized extract powder, 98% purified huperzine‑A crystal powder
‑ Appearance:1% extract: yellow‑brown fine powder; 98% purified: off‑white crystalline powder
‑ Test method:HPLC, chiral‑phase HPLC for isomer confirmation
‑ Particle size:95% pass 80 mesh; custom particle size available upon volume order
‑ Storage requirement:Sealed, cool‑dry environment, avoid strong light exposure
Request sample and original batch COA before you lock in bulk orders:duke@hongdaherb.com

Why Should You Buy Our Huperzine A Bulk Powder?
✅ Zero-dead-angle mixing technology in the 1% premix specification: Our 1% Huperzine A specification (optional) ensures extremely uniform distribution of active molecules in your Class 10,000 mixing workshop, completely eliminating the risk of finished product non-compliance caused by the "dosing black box."
✅ Extreme purity monitoring: Addressing the issue of easily introduced heavy metals, we have achieved extreme control of Pb < 0.2ppm and Cd < 0.1ppm, far exceeding conventional USP standards.
✅ HPLC-Verified Purity: Each batch fulfils USP/EP standards by HPLC and GC-MS testing.
✅ cGMP and ISO-Certified Production: Made in FDA 21 CFR Part 211 and EU GMP Annex 1 verified facilities.
✅ Global Regulatory Support: This includes DMF availability, CMC paperwork, and ICH stability data.
✅ Bulk Scalability: We can supply anything from clinical trials (50 kg) to commercial batches (5+ tonnes) in 3–7 days.

Product Parameters
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Item
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Specification Method
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Result
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Physical and Chemical Property
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||
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Appearance
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White fine Powder
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Conforms
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Particle Size
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≥95% through 80 mesh
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Conforms
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Residue on Ignition
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≤5g/100g
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0.28g/100g
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Loss on Drying
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≤5g/100g
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0.75g/100g
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Identification
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Conforms with TLC
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Conforms
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Content:
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Huperzine A>1%
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1.5%
|
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Residue Analysis
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||
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Heavy Metals
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≤10mg/kg
|
Conforms
|
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Lead (Pb)
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≤2.00mg/kg
|
Conforms
|
|
Arsenic (As)
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≤1.00mg/kg
|
Conforms
|
|
Cadmium (Cd)
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≤1.00mg/kg
|
Conforms
|
|
Mercury (Hg)
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≤0.010mg/kg
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Conforms
|
|
Microbiological Tests
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||
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Total Plate Count
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≤1000cfu/g
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150cfu/g
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Total Yeast & Mold
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≤100cfu/g
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45cfu/g
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E.Coli.
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Negative/10g
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Conforms
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|
Salmonella
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Negative/10g
|
Conforms
|
|
S.aureus
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Negative/10g
|
Conforms
|
|
Product Status
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||
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Conclusion:
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Sample Qualified.
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Send your inquiry, we attach latest actual‑batch lab data for your internal review:duke@hongdaherb.com
Raw Herb Sourcing & Our Production Reality
Huperzine A Bulk Powder is not an easy botanical material to source stably. It grows slowly in mountain areas, and over‑harvesting disturbs wild plant resources. We do not source random collected wild herbs. Our raw material comes from coordinated harvesting zones, with collection limits to avoid over‑picking. Every incoming plant lot goes through macroscopic botanical identification, and we retain raw sample archives for traceability purpose.
Lots of middlemen source generic crude herb, outsource extraction, and resell finished powder without full‑process oversight. We complete extraction, purification and crystallization in‑house at our Xi’an facility. That gives us full visibility over each production step, rather than relying on third‑party subcontractor test reports.

QC Workflow That Addresses Real‑World Sourcing Risks
Ordinary C18 HPLC cannot tell natural active (-)‑huperzine‑A apart from synthetic racemic isomer mix. Many suppliers only run standard HPLC and skip chiral verification, which creates hidden risk for your finished goods.
For every finished batch we deliver:
- Chiral HPLC test to confirm natural active isomer excess;
- Concentration assay via HPLC;
- Full heavy metal, residual solvent and microbial safety screening;
- Species identity check to rule out substitute plant material.
We never reuse universal template COAs. Each document corresponds strictly to your shipment batch number. Third‑party independent lab testing is fully acceptable if your market compliance requires external validation.

Bulk Order, Packing & Export Lead‑time
Lab‑scale evaluation samples are available; customer undertakes sample courier freight. Stock‑ready goods can ship within 10‑16 working days. Since Huperzia serrata raw material supply is subject to seasonal harvesting rhythm, we will proactively notify lead‑time changes ahead for large‑volume orders.
Standard export package: 25 kg fiber drum, double inner food‑grade PE moisture‑proof bags. Custom packing solution can be discussed for special project needs.

Some of its properties include:
Neuroprotective Mechanism: This reversible AChE inhibitor (IC₅₀ = 82 nM) increases cerebral acetylcholine and neuronal signaling. Huperzine A Bulk Powder inhibits NMDA receptors, lowers glutamate excitotoxicity, and protects neurons from oxidation.
Highly bioavailable: A single dose inhibits AChE for up to 6 hours across the blood-brain barrier.

Frequently Asked Questions
Q: What is the difference between your 1% extract and 98% purified huperzine‑A?
A: The 1% grade is total herb standardized extract, keeping other natural plant secondary metabolites. 98% grade goes through multi‑step purification to isolate high‑purity huperzine‑A crystal. Formulators pick grade according to finished‑product dosage design. We can offer reference formulation guidance.
Q: Can you guarantee all material is natural extracted, not synthetic racemic material?
A: We run chiral‑phase HPLC for each batch to verify natural (-)‑huperzine‑A isomer. Test records can be shared. Synthetic racemic huperzine‑A will fail our chiral‑spec requirement and will not be released for shipment.
Q: What documents can you provide for import clearance and brand audit?
A: ISO9001, Halal, Kosher certificates available on request. Every shipment comes with batch‑specific COA and MSDS. We do not supply medical‑related registration dossiers.
Q: How long is shelf‑life for huperzine‑A bulk powder?
A: 24 months under properly sealed cool‑dry storage. Direct sunlight, high humidity will speed‑up quality degradation.
Q: What is your MOQ?
A: Standard bulk MOQ is 25 kg for 1% extract; MOQ for 98% purified crystal is 1 kg. Small trial samples are open for pre‑production testing. Volume‑based discount applies for long‑term stable orders.
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Get Started Today
Submit Your Requirements:
- Purity grade (98% or 99%+)
- Quantity (kg to tons)
- Delivery deadline
Contact Our Experts:
Share your target market, desired grade and formulation goals. Our sales‑technical team will reply within 24 working hours.
📧 duke@hongdaherb.com | 📞 +86-13128890990
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