Huperzine A Bulk Powder

1.Botanical Source: Huperzia Serratum
2.Specification: Huperzine A 1％/99％
3.Test Method: HPLC
4.Appearance: White Fine Powder
5.CAS NO: 102518-79-6
6.Main Market: North America, Europe, Switzerland, South Africa, Southeast Asia, Australia, etc.
7.Packing specification: 12kg/drum, 27 drums/tray
8.Delivery: 3~7working days.
9.Certification: cGMP,FSSC,Kosher,Halal,BRC,Organic,FDA,ISO9001,ISO22000 etc.

Send Inquiry Download

Product Description

Premium Huperzine A Bulk Powder for Cognitive Health Formulations

When producing highly effective nootropic pills or seeking cognitive support, the quality and purity of the active ingredient are paramount. Our pure Huperzine A Bulk Powder, an acetylcholinesterase inhibitor, is ideal for B2B manufacturers and researchers. Huperzine A supplied by Shaanxi Hongda is a molecular-level raw material precisely separated from natural huperzine using multi-stage ultrafiltration and chiral chromatography. We ensure consistent stability across batches, providing you with an extremely high bioactivity window, whether it's 99% pure or pre-diluted 1% specifications.

This product comes as a bulk powder with a purity of 95% to 98%. It is a thin powder that is white to brown and easily dissolves in DMSO (30 mg/mL).

Huperzine A Bulk Powder

Some of its properties include:

Neuroprotective Mechanism: This reversible AChE inhibitor (IC₅₀ = 82 nM) increases cerebral acetylcholine and neuronal signaling. It inhibits NMDA receptors, lowers glutamate excitotoxicity, and protects neurons from oxidation.

Highly bioavailable: A single dose inhibits AChE for up to 6 hours across the blood-brain barrier.

Huperzine benefits

Why Should You Buy Our Huperzine A Bulk Powder?

✅ Zero-dead-angle mixing technology in the 1% premix specification: Our 1% Huperzine A specification (optional) ensures extremely uniform distribution of active molecules in your Class 10,000 mixing workshop, completely eliminating the risk of finished product non-compliance caused by the "dosing black box."

✅ Extreme purity monitoring: Addressing the issue of easily introduced heavy metals, we have achieved extreme control of Pb < 0.2ppm and Cd < 0.1ppm, far exceeding conventional USP standards.

✅ HPLC-Verified Purity: Each batch fulfils USP/EP standards by HPLC and GC-MS testing.
✅ cGMP and ISO-Certified Production: Made in FDA 21 CFR Part 211 and EU GMP Annex 1 verified facilities.
✅ Global Regulatory Support: This includes DMF availability, CMC paperwork, and ICH stability data.
✅ Bulk Scalability: We can supply anything from clinical trials (50 kg) to commercial batches (5+ tonnes) in 3–7 days.

certifications

Product Parameters

Item	Specification Method	Result
Physical and Chemical Property
Appearance	White fine Powder	Conforms
Particle Size	≥95% through 80 mesh	Conforms
Residue on Ignition	≤5g/100g	0.28g/100g
Loss on Drying	≤5g/100g	0.75g/100g
Identification	Conforms with TLC	Conforms
Content:	Huperzine A>1%	1.5%
Residue Analysis
Heavy Metals	≤10mg/kg	Conforms
Lead (Pb)	≤2.00mg/kg	Conforms
Arsenic (As)	≤1.00mg/kg	Conforms
Cadmium (Cd)	≤1.00mg/kg	Conforms
Mercury (Hg)	≤0.010mg/kg	Conforms
Microbiological Tests
Total Plate Count	≤1000cfu/g	150cfu/g
Total Yeast & Mold	≤100cfu/g	45cfu/g
E.Coli.	Negative/10g	Conforms
Salmonella	Negative/10g	Conforms
S.aureus	Negative/10g	Conforms
Product Status
Conclusion:	Sample Qualified.

Key Applications

Treatment for Alzheimer's: blocks acetylcholinesterase to enhance acetylcholine.
Nootropics improve memory and test scores in healthy people.
Neuroprotection formulas: decrease oxidative stress using resveratrol.

Quality Control and Compliance

Restrictive Testing

Class 1-3 residual solvents meet ICH Q3C criteria.
Pb, Hg, Cd, and As must be under 10 ppm (ICP-MS validated).
Microbial Safety: Meets USP <61> and <62> bioburden criteria.

Complete Traceability

Sustainable Huperzia serrata farms supply raw materials.
Batch-specific CoAs with third-party validation.

Quality assurance

Packaging and Delivery

The standard package size is 25 kg/drum, however you can get custom sizes. We make sure that your package gets to you quickly and safely by courier, air, or ocean freight.

Packaging and Delivery

Frequently Asked Questions

Q: Are your facilities cGMP certified?

A: Yes, we follow cGMP, ISO 9001, and ISO 13485 standards.

Q: May I request a customized CoA?

A: Yes, we provide batch-specific CoAs with residual solvent, heavy metal, and microbiological data.

Q: What is the lead time for 500 kg orders?

A: Standard delivery time: 5-7 days. Priority shipping is available.

Q: Do you support API-excipient blends?

A: Yes—we offer pre-mixed blends for direct compression (e.g., Huperzine A + mannitol).