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Huperzine A Bulk Powder

1.Botanical Source: Huperzia Serratum
2.Specification: Huperzine A 1%/99%
3.Test Method: HPLC
4.Appearance: White Fine Powder
5.CAS NO: 102518-79-6
6.Main Market: North America, Europe, Switzerland, South Africa, Southeast Asia, Australia, etc.
7.Packing specification: 12kg/drum, 27 drums/tray
8.Delivery: 3~7working days.
9.Certification: cGMP,FSSC,Kosher,Halal,BRC,Organic,FDA,ISO9001,ISO22000 etc.
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  • Product Description

Premium Huperzine A Bulk Powder for Cognitive Health Formulations

When producing high-potency nootropic pills or looking at cognitive support, active component quality and purity are most significant. Our pure Huperzine A Bulk Powder is ideal for B2B manufacturers and researchers. This versatile ingredient is ideal for creating cognitive health supplements, memory support products, and speciality nutraceuticals.

Huperzine A is an alkaloid that comes from the Chinese fern Huperzia serrata, which only grows in China. The chemical formula is C₁₅H₁₈N₂O, the molecular weight is 242.32, and the CAS number is 102518-79-6. 


This product comes as a bulk powder with a purity of 95% to 98%. It is a thin powder that is white to brown and easily dissolves in DMSO (30 mg/mL). 

Huperzine A Bulk Powder

Some of its properties are: 
Neuroprotective Mechanism: This reversible AChE inhibitor (IC₅₀ = 82 nM) boosts cerebral acetylcholine and neuronal signalling. It blocks NMDA receptors, reduces glutamate excitotoxicity, and protects neurones from oxidation. 
Highly bioavailable: One dose blocks AChE for up to 6 hours across the blood-brain barrier.

Huperzine benefits

 

Why Should You Buy Our Huperzine A Bulk Powder?

✅ HPLC-Verified Purity: Each batch fulfils USP/EP standards by HPLC and GC-MS testing. 
✅ cGMP and ISO-Certified Production: Made in FDA 21 CFR Part 211 and EU GMP Annex 1 verified facilities.
✅ Global Regulatory Support: This includes DMF availability, CMC paperwork, and ICH stability data.
✅ Bulk Scalability: We can supply anything from clinical trials (50 kg) to commercial batches (5+ tonnes) in 3–7 days.

Equipment

 

Product Parameters

Item
Specification Method
Result
Physical and Chemical Property
Appearance
White fine Powder
Conforms
Particle Size
≥95% through 80 mesh
Conforms
Residue on Ignition
≤5g/100g
0.28g/100g
Loss on Drying
≤5g/100g
0.75g/100g
Identification
Conforms with TLC
Conforms
Content:
Huperzine A>1%
1.5%
Residue Analysis
Heavy Metals
≤10mg/kg
Conforms
Lead (Pb)
≤2.00mg/kg
Conforms
Arsenic (As)
≤1.00mg/kg
Conforms
Cadmium (Cd)
≤1.00mg/kg
Conforms
Mercury (Hg)
≤0.010mg/kg
Conforms
Microbiological Tests
Total Plate Count
≤1000cfu/g
150cfu/g
Total Yeast & Mold
≤100cfu/g
45cfu/g
E.Coli.
Negative/10g
Conforms
Salmonella
Negative/10g
Conforms
S.aureus
Negative/10g
Conforms
Product Status
Conclusion:
Sample Qualified.


Key Applications

  • Treatment for Alzheimer's: blocks acetylcholinesterase to enhance acetylcholine.
  • Nootropics improve memory and test scores in healthy people.
  • Neuroprotection formulas: decrease oxidative stress using resveratrol.

 

Quality Control and Compliance

Restrictive Testing

  • Class 1-3 residual solvents meet ICH Q3C criteria.
  • Pb, Hg, Cd, and As must be under 10 ppm (ICP-MS validated).
  • Microbial Safety: Meets USP <61> and <62> bioburden criteria.

Complete Traceability

  • Sustainable Huperzia serrata farms supply raw materials.
  • Batch-specific CoAs with third-party validation.

Quality assurance

 

Packaging and Delivery

The standard package size is 25 kg/drum, however you can get custom sizes. We make sure that your package gets to you quickly and safely by courier, air, or ocean freight.

Packaging and Delivery

Our Certifications

Our certifications


Frequently Asked Questions

Q: Are your facilities cGMP-certified?

A: Yes, we adhere to cGMP, ISO 9001, and ISO 13485 standards.

Q: Can I request a customized CoA?

A: Absolutely—we provide batch-specific CoAs with residual solvent, heavy metal, and microbial data.

Q: What’s the lead time for 500 kg orders?

A: Standard delivery: 5-7 days. Priority shipping available.

Q: Do you support API-excipient blends?

A: Yes—we offer pre-mixed blends for direct compression (e.g., Huperzine A + mannitol).

 

Get Started Today

Submit Your Requirements:

  • Purity grade (98% or 99%+)
  • Quantity (kg to tons)
  • Delivery deadline

Contact Our Experts:

📧 duke@hongdaherb.com | 📞 +86-13128890990

Response guaranteed within 24 hours.​​​​​​​

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