Huperzine A Bulk Powder
2.Specification: Huperzine A 1%/99%
3.Test Method: HPLC
4.Appearance: White Fine Powder
5.CAS NO: 102518-79-6
6.Main Market: North America, Europe, Switzerland, South Africa, Southeast Asia, Australia, etc.
7.Packing specification: 12kg/drum, 27 drums/tray
8.Delivery: 3~7working days.
9.Certification: cGMP,FSSC,Kosher,Halal,BRC,Organic,FDA,ISO9001,ISO22000 etc.
- Product Description
Premium Huperzine A Bulk Powder for Cognitive Health Formulations
When producing high-potency nootropic pills or looking at cognitive support, active component quality and purity are most significant. Our pure Huperzine A Bulk Powder is ideal for B2B manufacturers and researchers. This versatile ingredient is ideal for creating cognitive health supplements, memory support products, and speciality nutraceuticals.
Huperzine A is an alkaloid that comes from the Chinese fern Huperzia serrata, which only grows in China. The chemical formula is C₁₅H₁₈N₂O, the molecular weight is 242.32, and the CAS number is 102518-79-6.
This product comes as a bulk powder with a purity of 95% to 98%. It is a thin powder that is white to brown and easily dissolves in DMSO (30 mg/mL).

Some of its properties are:
Neuroprotective Mechanism: This reversible AChE inhibitor (IC₅₀ = 82 nM) boosts cerebral acetylcholine and neuronal signalling. It blocks NMDA receptors, reduces glutamate excitotoxicity, and protects neurones from oxidation.
Highly bioavailable: One dose blocks AChE for up to 6 hours across the blood-brain barrier.

Why Should You Buy Our Huperzine A Bulk Powder?
✅ HPLC-Verified Purity: Each batch fulfils USP/EP standards by HPLC and GC-MS testing.
✅ cGMP and ISO-Certified Production: Made in FDA 21 CFR Part 211 and EU GMP Annex 1 verified facilities.
✅ Global Regulatory Support: This includes DMF availability, CMC paperwork, and ICH stability data.
✅ Bulk Scalability: We can supply anything from clinical trials (50 kg) to commercial batches (5+ tonnes) in 3–7 days.

Product Parameters
Item | Specification Method | Result |
Physical and Chemical Property | ||
Appearance | White fine Powder | Conforms |
Particle Size | ≥95% through 80 mesh | Conforms |
Residue on Ignition | ≤5g/100g | 0.28g/100g |
Loss on Drying | ≤5g/100g | 0.75g/100g |
Identification | Conforms with TLC | Conforms |
Content: | Huperzine A>1% | 1.5% |
Residue Analysis | ||
Heavy Metals | ≤10mg/kg | Conforms |
Lead (Pb) | ≤2.00mg/kg | Conforms |
Arsenic (As) | ≤1.00mg/kg | Conforms |
Cadmium (Cd) | ≤1.00mg/kg | Conforms |
Mercury (Hg) | ≤0.010mg/kg | Conforms |
Microbiological Tests | ||
Total Plate Count | ≤1000cfu/g | 150cfu/g |
Total Yeast & Mold | ≤100cfu/g | 45cfu/g |
E.Coli. | Negative/10g | Conforms |
Salmonella | Negative/10g | Conforms |
S.aureus | Negative/10g | Conforms |
Product Status | ||
Conclusion: | Sample Qualified. | |
Key Applications
- Treatment for Alzheimer's: blocks acetylcholinesterase to enhance acetylcholine.
- Nootropics improve memory and test scores in healthy people.
- Neuroprotection formulas: decrease oxidative stress using resveratrol.
Quality Control and Compliance
Restrictive Testing
- Class 1-3 residual solvents meet ICH Q3C criteria.
- Pb, Hg, Cd, and As must be under 10 ppm (ICP-MS validated).
- Microbial Safety: Meets USP <61> and <62> bioburden criteria.
Complete Traceability
- Sustainable Huperzia serrata farms supply raw materials.
- Batch-specific CoAs with third-party validation.

Packaging and Delivery
The standard package size is 25 kg/drum, however you can get custom sizes. We make sure that your package gets to you quickly and safely by courier, air, or ocean freight.

Our Certifications

Frequently Asked Questions
Q: Are your facilities cGMP-certified?
A: Yes, we adhere to cGMP, ISO 9001, and ISO 13485 standards.
Q: Can I request a customized CoA?
A: Absolutely—we provide batch-specific CoAs with residual solvent, heavy metal, and microbial data.
Q: What’s the lead time for 500 kg orders?
A: Standard delivery: 5-7 days. Priority shipping available.
Q: Do you support API-excipient blends?
A: Yes—we offer pre-mixed blends for direct compression (e.g., Huperzine A + mannitol).
Get Started Today
Submit Your Requirements:
- Purity grade (98% or 99%+)
- Quantity (kg to tons)
- Delivery deadline
Contact Our Experts:
📧 duke@hongdaherb.com | 📞 +86-13128890990
Response guaranteed within 24 hours.
Trusted by Top 20 Pharma Companies | FSSC 22000 & Kosher Certified | Confidentiality Assured


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