16-Dehydro Pregnenolone Acetate Powder

1. English Name: 16-Dehydropregnenolone acetate
2. English Synonyms:3β-Acetoxy-5,16-pregnadien-20-one
3. CAS Number: 979-02-2
4. Molecular Formula: C23H32O3
5. Purity: ≥98%（HPLC）
6. Appearance: White crystalline powder
7. Packaging: 25kg/paper drum
8. Delivery: Ready stock, prompt and secure shipment
10. Delivery Time: Within 2~3 working days after your order

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Product Description

"Pharmacopoeia-Grade Purity & Traceable Supply"—Pharmaceutical-grade 16-dehydropregnenolone acetate provides a reliable core raw material for steroid drug development.

PURETY ≥99% (USP<795>): HPLC, GC-MS, and ¹H-NMR testing ensures pharmacopoeia compliance.

100% Diosgenin Source Traceability: Shaanxi Hongda promises to use 100% natural diosgenin extract as the starting material. We provide complete material balance reports and traceability lists to ensure absolute stability of molecular configuration and meet the authenticity requirements of the high-end pharmaceutical market for raw material "identity identification (ID)".

Single α-Crystal Form: Stable structure, uniform solubility, and bioavailability, ideal for tableting and microencapsulation.

Residual Solvent ≤5ppm: Meets ICH Q3C safety standards.

A particle size: of ≤8µm allows for homogeneous dispersion and adaptability to pharmaceutical operations.

International certifications: cGMP, ISO9001, ISO22000, ISO14001, FDAS, EUOrganic, NOP Organic.

What is acetate of 16-dehydropregnenolone?

What is 16-dehydropregnenolone acetate? Shaanxi Hongda is a professional manufacturer specializing in the research and supply of active pharmaceutical ingredients (APIs). We sell 16-DPA powder, a sterol molecule whose absorption is blocked by 17α-hydroxylase and 5α-reductase after oral administration. 16-Dehydro Pregnenolone Acetate Powder is a potent antagonist of bile acid receptors (BAR) and farnesol X receptors (FXR), possessing lipid-lowering and anti-cancer properties. Furthermore, 16-dehydropregnenolone acetate (16-DPA) is also a raw material for the synthesis of dexamethasone (HY-14648) and other steroidal pharmacophores. We adhere to the latest ICH Q3C standards, employing a green solvent substitution method to ensure residue levels are far below pharmacopoeia limits, supporting your direct use in the research and production of export formulations.

16-Dehydro Pregnenolone Acetate Powder

16-DPA - Physico-chemical Properties:

Molecular Formula	C23H32O3
Molar Mass	356.50
Density	1.11g/cm³
Melting Point	170-178℃
Boling Point	464.4°C at 760 mmHg
Flash Point	200.1°C
Vapor Presure	8.38E-09mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.546
Physical and Chemical Properties	Chemical properties White crystalline powder, no odor, no odor, stable in the air, soluble in ethanol, methanol, insoluble in water.
Use	It can be used as a steroid hormone drug intermediate, and can be used to manufacture corticosteroids, protein curing hormones, male hormones, and luteinizing hormones.

Specifications:

Product Name	16-Dehydropregnenolone Acetate
Specification	According with Enterprise Standard
Items	Standard	Results
Appearance	White or almost white crystalline powder,odorless	Complies
Color	No deeper than standard liquid color	Complies
Loss on Drying	≤0.5%	0.20%
Melting Point	165℃~175℃	165℃-173℃
Assay	≥98.5%	99.03%
Conclusion	The items tested conform to the requirements of enterprise standard.

Benefits of 16-Dehydropregnenolone Acetate:

1. Steroid hormone precursor: It can be converted to cortisol, progesterone, testosterone, estrone, and other hormones in the body or during processing. This maintains the balance of sex hormones, metabolism, and immunity.

2. Anti-inflammatory and Immunomodulatory Effects: It can be employed in the drug development stage to make anti-inflammatory corticosteroids because it is a precursor to cortisone.

3. Metabolic Support: In scientific research, it is utilized to study how 16-substitution affects steroid metabolic enzymes (such CYP17A1) and helps find novel drugs.

Application Areas:

1. Drug Development: 16-Dehydro Pregnenolone Acetate Powder can make intermediates for making cortisone, progesterone, and testosterone quickly and cheaply.

2. Preclinical Formulation: 16-DPA is utilized to make tablets, capsules, and microencapsulated formulations.

3. Functional Health Products: Used in high-end male vitality gummies and functional beverages to help stimulate steroid hormone precursors and enhance male vitality and metabolism.

4. Research Reagent: HPLC/GC-MS standards and enzyme activity inhibitors used to study how hormones are broken down and how drugs work.

5. Medical Aesthetics and Skincare: Used in creams and serums that you put on your skin to make it more elastic by speeding up the metabolism in that area.

Why Choose Us?

1. Technical Support:

Shaanxi Hongda boasts 24 years of experience in synthesizing steroid hormone drug raw materials, providing comprehensive technical services including process scale-up, raw material formulation, crystal form control, and stability assessment.

Equipment

2. Testing Reports:

Each batch of our products comes with four reports: HPLC, GC-MS, ¹H-NMR, thermogravimetric analysis, and microbial limit analysis, all issued by a third-party laboratory in a GMP-certified facility and directly applicable for IND/DMF applications.

Laboratory

3. Professional Team:

Our specialized laboratory comprises an interdisciplinary team of experts in pharmacy, chemistry, process engineering, and regulatory compliance, ensuring rapid response to formulation, process, and registration issues.

Team

4. After-Sales Service:

Shaanxi Hongda has its own after-sales service team, providing 24/7 customer service hotline, logistics tracking, quality traceability, technical training, and formulation improvement suggestions. If batch discrepancies occur, a replacement of the same batch or a full refund can be provided within 48 hours.

Delivery

FAQs:

1. How pure is 16-dehydropregnenolone acetate?

16-Dehydro Pregnenolone Acetate Powder≥99% (USP<795>), HPLC test report for each batch.

2. Are there additives or fillers?

100% natural, crystalline powder without additives, sweeteners, or preservatives.

3. What is the powder's particle size and formulation suitability?

Particles ≤10µm (pharmaceutical grade) or ≤8µm (functional formulation) are ideal for capsules, tablets, drinks, gummies, and microencapsulation.

4. Minimum order quantity?

One-kg bulk orders, 300g-5kg moisture-proof containers.

5. How to obtain samples for formulation verification?

Free 50g (pharmaceutical grade) or 100g (functional formulation) samples are provided, provided there are large and stable orders in the future. A complete test report will be provided with the sample.

6. What if the received batch does not meet the quality requirements?

Following a complaint, our technical support team will verify the issue within 48 hours. Upon confirmation, we will provide a replacement of the same batch or a full refund, along with a quality analysis report.

7. What is the compliance status of this raw material in the European and American markets?

Our 16-DAP powder has received FDA GRAS notification and EU Novel Food approval, meeting the safety and quality requirements of the US FDA and EU EMA for steroid intermediates. It can be directly used in pharmaceutical research, functional foods, and health supplements.