Citicoline Powder
2、Specification:99% HPLC
3、Appearance: White Crystalline Powder
4、CAS NO.: 33818-15-4
5、Lead time: 3-7 Working Days
6、Package: 25kg/drum, 27 drums/tray
7、Main Market: Europe, America, Vietnam, Indonesia, Southeast Asia, Thailand, Russia, etc.
8、Certification: cGMP,Kosher, Halal, BRC, Organic, ISO9001, ISO22000, etc
9、Europe Warehouse/America Warehouse
- Product Description
Bulk Citicoline Powder (CDP-Choline) Nutraceutical Raw Material | Hongda Phytochemistry
Citicoline supplier/Citicoline powder factory/Citicoline powder manufacturers
Are you seeking for pharmaceutical-grade china Citicoline Powder that fulfills the highest standards in the industry? Our high-quality Citicoline is exceptionally pure (≥99%) and consistent, making it perfect for your brain medication research and nutritional manufacturing requirements. Our citicoline bulk powder is one of our high-volume stable stock raw materials, widely sourced by supplement manufacturers, private label brands and formulation labs across North America, Europe and Southeast Asia.
We are a cGMP-certified supplier you can trust, and we provide this crucial neuroprotective substance with all the relevant papers and a guarantee of quality. Our Citicoline makes sure that your goods work well and are safe, whether you're creating medications to assist patients recover from strokes or supplements to make their brains work better.
Factory price citicoline (CDP-Choline, CAS: 987-78-0) is a brain molecule that helps cells repair their membranes and utilize energy. This crucial phospholipid precursor helps preserve neurons and make the brain work better in a lot of different types of therapy.

Request Samples|Download Spec Sheet
Why Buy Citicoline Powder From Hongda Phytochemistry?
Citicoline, or CDP-Choline, is a molecule that occurs naturally in the body. It helps create neurotransmitters and speeds up the synthesis of cell membranes:
1. Strict residual solvent & impurity control
Residual solvent is a major concern for supplement factories. Our purification process follows ICH Q3C requirements. We provide residual solvent test data for every batch for your quality review.
2. Stable batch consistency, less color variation
We keep tight process parameters during recrystallization. Our customers see fewer color differences between batches, which simplifies your blending and finished batch quality control.
3. Reliable large-volume supply capacity
This is our regular fast-moving raw material. We hold inventory buffer and stable monthly output. We support repeated bulk orders and full container shipments. Pre-production sample confirmation is available for large projects.
Product Specification
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Item of Test
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Limits of Test
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Results of Test
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Appearance
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White crystalline or crystalline powder
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Conform
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Assay by HPLC
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≥98%
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99.85%
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Identification
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(1)A green colour is produced
(2)The retention time of the principal peak in the chromatogram obtained with the test solution is identical with that of the principal peak in the chromatogram obtained with the reference solution
(3)The infrared absorption spectrum is concordant with the standard spectrum.
(4)The aqueous solution yields the reaction (1)characteristic of sodium salts.
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Complies
Complies
Complies
Complies
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pH
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6.0---7.5
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6.9
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Clarity, color of solution
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Clear, colorless
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Complies
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Chloride
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≤0.05%
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Complies
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Ammonium salt
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≤0.05%
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Complies
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Iron salt
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≤0.01%
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Complies
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Phosphate
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≤0.1%
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Complies
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Related substances
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5'-GMP≤0.3%
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0.006%
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Single impurity ≤0.2%
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0.006%
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Total Another Impurity≤0.7%
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0.02%
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Residual solvents
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Limit of methanol≤0.3%
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Undetected
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Limit of ethanol≤0.5%
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Undetected
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Limit of acetone≤0.5%
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Undetected
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Loss on drying
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≤6.0%
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0.8%
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Heavy Metals
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≤5ppm
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Complies
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Arsenic salt
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≤0.0001%
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Complies
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Endotoxin
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<0.30EU/mg
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Complies
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Limit of microbe
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Total bacterial count≤1000 CFU/g
Yeast & Mold≤100 CFU/g
E. Coli: Negative
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< 10 CFU/g
< 10 CFU/g
Undetected
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Conclusion
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The product meets with the CP2020 standard.
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If you have questions about impurity limits or document requirements for your target market, send us your inquiry:duke@hongdaherb.com
Core Manufacturing & Purification Process
Most quality complaints for CDP-Choline Powder come from incomplete purification, poor solvent removal and inconsistent recrystallization. Our process is designed to solve these common manufacturing risks:
- Raw material incoming inspection Check identity and impurity levels of all starting materials before synthesis. Any non-compliant raw batches get rejected immediately.
- Controlled synthesis reaction Run reaction under stable temperature and pH environment to reduce by-product generation.
- Multi-step purification & recrystallization Multiple rounds of purification to remove reaction by-products and residual solvents, following ICH solvent limits.
- Drying and milling Low-temperature drying to avoid product degradation, then milling and sieving to control particle size, reduce static electricity for easier capsule filling.
- Full batch quality testing Each batch tests identity, purity, loss on drying, heavy metals, residual solvent and microbial indicators.
- Sealed moisture-proof packaging Pack drums quickly after QC pass. Extra protection can be arranged for long sea shipment to humid areas.
Key Applications & BenefitsWhat Makes Citicoline Powder Essential for Brain Health?
Stroke Recovery: Accelerates neural repair in post-stroke medications.
Cognitive Enhancement: It helps with memory and focus in nootropic drugs.
Neurodegenerative Support: Used in Alzheimer’s and dementia formulations.
Our Citicoline (CAS 987-78-0) dissolves in water, therefore it works best in tablets, capsules, or liquid mixtures.

Applications
Pharmaceutical Applications
Wholesale citicoline powder is an important part of drugs that help people with Alzheimer's and strokes. Studies on people have shown that it helps brain cells grow back and reduces nerve inflammation. Our pharmaceutical-grade components may help you create innovative nerve therapies that are safe and effective according to FDA and EMA requirements.
Nutraceutical Applications
The growing brain health supplement market demands high-quality factory price citicoline for nootropic formulations. Your users will be able to recall things better, focus better, and think more clearly. Our substance is safe to ingest and works well with pills, tablets, and liquid vitamins, among other delivery methods.
Important note:Buyers are responsible for verifying local import regulations and finished-product labeling rules for your target market. We cannot guarantee customs clearance results.
What Our Clients Say
“Their Citicoline cytidine diphosphate choline powder met our strict pharma-grade specs. Seamless compliance support!”
– Dr. Elena M., Neurological Pharma Brand (Spain)
“Consistent quality and competitive pricing for our nootropic line.”
– James T., Supplement Manufacturer (USA)

Quality Certifications
Bulk Citicoline cytidine diphosphate choline powder manufacturing facility maintains the highest quality standards through comprehensive certifications. Our production methods are pharmaceutical-grade because we have cGMP approval. ISO 9001 and ISO 13485 are examples of certifications that ensure quality control systems are always the same. USP and EP monograph compliance provides regulatory confidence for global markets.

Assurance Quality
Every lot goes through a lot of testing by a third party, and they get full Certificates of Analysis (CoA). To help you with your regulatory applications, we give you detailed paperwork like Material Safety Data Sheets (MSDS) and Drug Master Files (DMF).

Why Partner With Us?
- ✅ 25+ Years Expertise: Trusted by 200+ global brands.
- ✅ Scalable Production: From 5kg to 20-ton batches.
- ✅ Fast Global Shipping: Doorstep delivery with cold-chain options.
- ✅ 24/7 Technical Support: Formulation guidance and market insights.

Frequently Asked Questions
1: What is the purity grade of your citicoline?
A: Our standard citicoline purity ≥99%. Exact value is shown on each lot’s COA. Custom specifications can be discussed.
2: How do you control residual solvent in citicoline?
A: We adopt multi-step recrystallization purification. Each batch runs residual solvent test complying with ICH Q3C guidelines. Test reports can be shared for your quality audit.
3: Does citicoline create static problems during capsule filling?
A: Fine crystalline citicoline may generate static. Our controlled particle size helps reduce this issue. We recommend small formulation trials before mass production, as workshop humidity also impacts powder performance.
4: What documents will I get for bulk shipment?
A: Lot-matched COA, heavy metal test report, microbial report and SDS are standard. Kosher, Halal or other certificates need advance confirmation. Buyers need to check local import rules independently.
5: What’s the shelf life of your Citicoline?
Stable for 24+ months when stored in sealed containers at <25°C.
6: Do you offer samples?
Yes – free samples for qualified buyers.
7: What’s the MOQ?
5kg for nutraceuticals; 25kg for pharma projects.
8: Is it suitable for vegan products?
Absolutely – synthetic, allergen-free, and cruelty-free.
Get Started Today
Are you ready to make you use Hongda Phytochemistry's Citicoline Powder of the best quality? Our team of experts is ready to talk to you about your specific needs and come up with solutions that work for you.
For samples, wholesale discounts, and comprehensive product information, contact our legal and technical specialists at duke@hongdaherb.com. Let us help you bring innovative neurological products to market with confidence and speed.