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Semaglutide Powder

1.Name:Semaglutide
2.Appearance:white powder
3.Specification:99%
4.CAS No.:910463-68-2
5.Molecular Formula:C187H291N45O59
6.Certificates: FDA,Organic,Kosher, ISO, HALAL, FSSC, cGMP
7.Transport Package:1kg Aluminum Foil Bag/25kg Drum
8.Factory situation:Factories & Three production lines.cGMP standard workshop & two independent laboratories.
9.Storage method:Dry and cool place

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  • Product Description

Semaglutide Powder: The Next-Generation GLP-1 Raw Material for Precise Blood Glucose Regulation and Weight Management

Semaglutide Raw Powder Factory(semaglutide powder supplier)– China's Most Professional Raw Material Supplier

1. 24 Years of Experience in API R&D and Production: Since its establishment in 2001, the company has focused on the process R&D and large-scale production of peptide, nucleic acid, and small molecule APIs, serving over 350 domestic and international pharmaceutical companies.

2. Full-Chain Compliance System: Hongda's products have passed multiple certifications including cGMP, ISO9001, ISO22000, Halal, Kosher, FDA, EU, and NOP, allowing direct entry into major pharmaceutical markets such as the US, EU, Japan, and Australia.

3. Self-Built High-Efficiency Continuous Mobile Phase Platform: We possess 12 10L-200L continuous mobile phase synthesis units, an ultra-low temperature vacuum freeze-drying system, and a fully automated packaging line, with an annual production capacity of 1.2kt of peptide raw materials. This eliminates the distributor link, enabling direct factory pricing.

4. Customized Service Capabilities: We can offer personalized services based on what the customer needs, such as purity gradients (95% to 99.5%), micronization, anhydrous freeze-drying, OEM private labeling, and multi-specification packaging (glass bottles, aluminum foil bags, vacuum jars). This helps customers quickly make their formulas stand out.

 

What is Semaglutide?

Semaglutide powder is a long-acting GLP-1 receptor agonist peptide that effectively stabilizes blood sugar levels and reduces weight. The pure Smegglutide powder we provide has a purity ≥98% (LC-MS), residual solvent ≤5ppm, and moisture ≤0.5%. Its activity remains unchanged after 24 months of cold chain storage at 2°C–-8°C. It has passed safety and pharmacokinetic evaluations by the FDA, EMA, and PMDA, and can be used in GLP-1 drug development, clinical blood sugar reduction, and functional weight-loss foods.

 Semaglutide powder

Product Specification

TEST
SPECIFICATION
RESULT
1
Appearance
White or almost white loose powder
Conforms
2
Solubility
Freely soluble in water
Conforms
3
Related Substance
Any individual impurity: ≤2%
0.2%
4
Identification by MS
4113.58±1
Conforms
 
 
5
 
 
Identification by HPLC
The  retention time of the  principal peak of the test solution corresponds to that of the reference solution, as obtained in the Assay
Conforms
6
Water Content (K.F)
8.0%
3.3%
7
Peptide Purity (By HPLC)
≥ 98.0%
99.6%
8
pH
7.0-9.0
7.6
9
Sodium ion
1.5-4.0%
2.0%
10
Solution clarity and color
Clear and colorless
Conforms
11
High molecular protein
0.5%
0.03%
12
Residual solvents
Methylene chloride<600ppm
Acetonitrile<410ppm
Methanol<3000ppm
N,N-Dimethylformamide<880ppm
Isopropyl ether<5000ppm
Isopropanol<5000ppm
N.D
20ppm
8ppm
N.D
4ppm
35ppm
13
Acid group Ions
Trifluoroacetate ion<1000ppm
Phosphate ion<1000ppm
Chloride ion<1000ppm
Acetic acid<1000ppm
N.D
0.02%
N.D
N.D
14
Specific Optical Rotation
-15.0~-10.0 o [α ] 20D
(anhydrous   and   acetic   acid   free substance ,C=10mg/ml,H2O)
 
-11.8o
15
Assay
95.0~105.0%, Calculated  with  reference to the anhydrous and salt-free substance
100.4%
Conclusion: This batch of product complies with enterprise standard. Used only for research. Keep in tight container, protected from light, store at -20℃.

 

Advantages of Semaglutide:

1. High Purity, Low Residue: Hongda's Semaglutide Powder meets global pharmaceutical safety requirements with a purity of ≥98% and residual organic solvents of ≤5ppm.

2. Long-Lasting Glycemic Regulation: Semaglutide Bulk Powder has a half-life of around a week, which makes it easier for patients to take it once a week.

3. Lyophilized Powder: Hongda's ultra-low temperature lyophilization process keeps the peptide chain structure stable, making it easier to move over long distances and store in a cold chain.

4. Guaranteed Safety: The FDA, EMA, and PMDA have all tested Semaglutide weight loss and found it to be safe. It can be given in a number of ways, such as by injections, nasal sprays, and oral microencapsulation.

5. Full Testing Reports: Each batch comes with a full Certificate of Analysis (COA) that includes LC-MS, MS-MS, amino acid sequence, bacteria, endotoxins, and residual solvents. This makes it easy to trace.

 

Functions and Uses of Semaglutide:

1. Diabetes Drug Development: Research indicates that semaglutide raw powder is a core ingredient for diabetes treatment, capable of regulating blood sugar and reducing weight.

2. Functional Foods/Dietary Supplements: Low doses (≤0.5mg) added to high-end health drinks and softgels to help boost metabolism and reduce weight.

3. Combination Therapy: Can be used in combination with SGLT2 inhibitors, DPP-4 inhibitors, etc., to form a multi-target synergistic treatment plan.

semaglutide powder benefits

Why to buy semaglutide powder?

1. Factory Direct Supply, Transparent Pricing:

As one of China's most professional raw material factories, Shaanxi Hongda eliminates middlemen, offering the most competitive factory prices.

Laboratory

2. Complete Certifications:

Hongda's products have passed multiple certifications including ISO, cGMP, Kosher, HALAL, and FDA, and provide COA.

Certifications

3. Fast Delivery:

We have a cold chain logistics system; regular orders are shipped within 5-7 days, and urgent orders can be expedited.

Packaging

4. Flexible Customization:

We can customize everything from purity and dosage to packaging and private labeling to help products achieve competitive differentiation.

OEM service

FAQs:

Q1: What are the differences between Semaglutide and Retatrutide?

A: Smegglutide only activates the GLP-1 receptor, making its action relatively singular; Retatrutide activates three receptors simultaneously—GLP-1, GIP, and Glucagon—resulting in greater weight loss, but its development is also more difficult and costly.

Q2: What are the storage conditions for the product?

A: It is recommended to store in a cold chain at 2°C–8°C, avoiding repeated freeze-thaw cycles. Unopened lyophilized powder can maintain its activity for 24 months at 4°C–20°C.

Q3: Is anhydrous packaging available?

A: Yes. We provide vacuum lyophilized bottles and nitrogen-filled aluminum foil bags to ensure the powder remains dry for extended periods.

Q4: Can this peptide be taken orally?

A: Oral delivery (≤0.5mg) is conceivable using microencapsulation or liposome packing, and functional beverage experiments have been completed.

Q5: Has your batch been certified organic or GMP-Free?

A: Yes. We can deliver GMP-Free (non-pharmaceutical) or organic-compliant raw materials with prior notice.

Q6: Which product safety data is available?

A: We report microbiological limits, endotoxins (≤0.05 EU/mL), residual solvents, amino acid sequence confirmation, and in vitro cytotoxicity (IC₅₀>10µM) for each batch.

Q7: Delivery time?

A: Standard inventory ships in 5-7 business days; customized packaging or certification adds 2-3 days.

Q8: Will the delivery time be affected if OEM private label is required?

A: Private label packaging generally adds 2-3 days to the standard delivery time, the specific time depending on the label design and packaging specifications.

Q9: Can you provide samples for formulation validation?

A: We offer a 100mg trial pack, complete with a COA and SDS. The first sample is free (company certification required).

Q10: Will this peptide affect the pH in the formulation?

A: Semaglutide maintains structural stability within a pH range of 3-9 and is not degraded by conventional heat treatment (≤80°C), making it safe for use in most formulation systems.

 

Contact us:

Email: duke@hongdaherb.com
Tel: +86-131 2889 0990
WeChat/WhatsApp: +86-131 2889 0990

Shaanxi Hongda is semaglutide raw powder factory/china semaglutide raw powder factory/china semaglutide raw powder manufacturers/semaglutide raw powder suppliers,and we always adheres to the principle of "Quality First, Service Supreme," providing global partners with safe, reliable, and efficient Semaglutide Powder to help your products stand out in a highly competitive market.

Semaglutide Powder Supplier

 

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